THE LANDSCAPE OF NOVEL THERAPEUTICS AND CHALLENGES IN GLIOBLASTOMA MULTIFORME: CONTEMPORARY STATE AND FUTURE DIRECTIONS

The Landscape of Novel Therapeutics and Challenges in Glioblastoma Multiforme: Contemporary State and Future Directions

Background: Glioblastoma multiforme is a malignant intracranial neoplasm that constitutes a therapeutic challenge because of the associated high morbidity and mortality given the lack of effective approved medication and aggressive nature of the tumor.However, there has been extensive research recently to address the reasons implicated in the resis

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Psychomotor Retardation in untreated depressed elderly

Background: Psychomotor retardation (PR) is one of the core features in depression according to 17 DSM V1, but also aging in itself causes cognitive and psychomotor slowing.This is the first study 18 investigating psychomotor retardation in relation to cognitive functioning and to the concomitant 19 effect of depression and aging in a geriatric pop

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